Metabolic fate and effects of saturated and unsaturated fatty acids in Hep2 human larynx tumor cells
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چکیده
منابع مشابه
Combined effect of unsaturated fatty acids and saturated fatty acids on the metabolic syndrome: tehran lipid and glucose study
AIMS The aim of this study was to investigate whether the background intakes of total dietary fat, monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) modulate the effects of dietary saturated fatty acids (SFA) on metabolic syndrome (MetS). MATERIAL AND METHODS This population-based cross-sectional study was conducted on a representative sample of 4,677 adults, aged 19 t...
متن کاملIsolation and determination methods for brain cerebrosides, hydroxy fatty acids, and unsaturated and saturated fatty acids *
A new method is described for the isolation of nearly pure total cerebrosides from fresh brain. Florisil columns are used to separate the cerebroside hydroxy and normal acids, in the form of their esters, and to separate the saturated and unsaturated esters of each group. The esters within each class are determined by gas chromatography, the hydroxy esters being run as the methyl ethers. Yields...
متن کاملMetabolic Effects of Polyunsaturated Fatty Acids in Chickens: A Review
Chicken has been used as a suitable model for lipid metabolism studies, because dietary modifications especially dietary fat type can change chicken body composition. Fats act as a condense source of energy and certain fatty acids such as polyunsaturated fatty acids (PUFAs) are required for both animal and human health. The n-3 PUFAs, especially, eicosapentaenoic acid (EPA) and docosahexaenoic ...
متن کاملAntagonism Between Saturated and Unsaturated Fatty Acids in ROS Mediated Lipotoxicity in Rat Insulin-Producing Cells.
BACKGROUND/AIMS Elevated levels of non-esterified fatty acids (NEFAs) are under suspicion to mediate β-cell dysfunction and β-cell loss in type 2 diabetes, a phenomenon known as lipotoxicity. Whereas saturated fatty acids show a strong cytotoxic effect upon insulin-producing cells, unsaturated fatty acids are not toxic and can even prevent toxicity. Experimental evidence suggests that oxidative...
متن کاملOpposite effects of saturated and unsaturated free fatty acids on intracellular signaling and metabolism in neuronal cells
Elevated levels of plasma saturated free fatty acids are a major pathogenic factor in diabetes, cardiovascular and liver diseases. Growing evidence suggests a link between sFFA-induced metabolic impairments and neurodegeneration. Excessive sFFAs in the brain circulation may trigger neuroinflammation and insulin resistance, however the underlying signaling changes have not been clarified in neur...
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ژورنال
عنوان ژورنال: IUBMB Life
سال: 1997
ISSN: 1521-6543
DOI: 10.1080/15216549700201631